在药物制剂的研究和生产过程中，提高患者顺应性、改善药物疗效及保证药物稳定，是药剂学发展的主要目标。而将药物定时、定向、高效运送到确定靶点，亦显得至关重要。目前控制药物释放的方法主要有两个，一为物理方式，包括扩散、侵蚀、渗透泵；二为化学方式，包括多聚物- 药物偶合物、
In the research and production process of pharmaceutical preparations, the main goal of pharmaceutical development is to improve patients' compliance, improve drug efficacy and ensure drug stability. It is also very important to transport the drug to a certain target in time, orientation and efficiency. At present, there are two main methods to control drug release, one is physical mode, including diffusion, erosion, osmotic pump; the other is chemical mode, including polymer drug coupling
药物共轭物、离子交换。随着多学科的交叉渗透发展，离子交换树脂作为药物载体越来越多地被应用在药剂学方面。作为一种新兴药物载体，它通过离子交换的方式将药物释放到患者体内。近些年来，因离子交换树脂具有特殊的纳微界面结构[1]，及其在药剂学方面的潜在应用价值，引起了广泛地关注。鉴于酸性和碱性药物都可以吸附分散在离子交换树脂内部的特点，使其衍生了诸多优点，如掩盖药物的不良味道、促进难溶性药物的溶出、提高药物在贮存环境及体内溶出的稳定性、控制药物缓慢释放等。部分制剂在利用离子交换树脂技术后，甚至会集合上述优点中的多种。
Drug conjugates, ion exchange. With the development of interdisciplinary permeation, ion exchange resin as drug carrier is more and more used in pharmaceutics. As a new drug carrier, it releases drugs to patients through ion exchange. In recent years, due to the special nano micro interface structure of ion exchange resin and its potential application value in pharmaceutics, it has attracted extensive attention. In view of the characteristics that both acidic and alkaline drugs can be adsorbed and dispersed in the ion exchange resin, it has derived many advantages, such as covering up the bad taste of drugs, promoting the dissolution of insoluble drugs, improving the stability of drug dissolution in the storage environment and in vivo, controlling the slow release of drugs, etc. Some preparations will even integrate many of the above advantages after using the ion exchange resin technology.